Bosses

Bosses are very strong monsters found in boss rooms at the end of a floor. The boss at the end of the floor must be defeated in order to advance to the next floor. In later chapters, bosses are able to spawn as normal enemies. This starts in the caves, where the Gurglings are often encountered. The boss for a particular floor is chosen from the pool of bosses for the environment of the floor. Bosses may also spawn as champions, which can change various attributes such as health, damage, and attack pattern. Upon defeat, most bosses will drop an item from the boss item pool.

Bosses boast additional resistances to status effects. For example, fear occurs less often and the Night Light is unable to slow them down.

Additionally, some floors may spawn a room with a Mini-Boss. Team Genesis + is working on new bosses that fit with Isaac thematically and these new Chapters, these are currently the bosses you will face in the new content as well as new Bosses that we add to normal chapters.

Note : The Bosses Template is outdated as of yet.

Bosses who'm are not in the game can still be seen in the drop menu below everything.